Package: titeIR 0.1.0

titeIR: Isotonic Designs for Phase 1 Trials with Late-Onset Toxicities

Functions to design phase 1 trials using an isotonic regression based design incorporating time-to-event information. Simulation and design functions are available, which incorporate information about followup and DLTs, and apply isotonic regression to devise estimates of DLT probability.

Authors:Lee McDaniel [aut, cre]

titeIR_0.1.0.tar.gz
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titeIR.pdf |titeIR.html✨
titeIR/json (API)

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2 exports 0.36 score 1 dependencies 1 mentions 2 scripts 136 downloads

Last updated 6 years agofrom:fa48672da9. Checks:OK: 7. Indexed: yes.

Exports:isotitedoseisotitesim

Dependencies:Iso